Tyrosinase Inhibition Activity of Lycium Barbarum Extract

Abstract

The melanin pigment is an important for protection the skin from UV rays . tyrosinase enzyme is limiting step in the production of melanin, over production of melanin may cause multiple skin conditions, such as sun melanosis, ephelides, melasma, senile lentigosis, and postinflammatory hyperpigmentation. So that tyrosinase inhibitors can be useful in skin depigmentation. Tyrosinase inhibitor from natural sources gain an interest because they are thought to have less negative side effects. L. barbarum, belong to Solaneseae family, which is thought to be a botanical species with medicinal qualities. Scientifically termed fructus Lycii and cortex Lycii radicis,. L. barbarum fruits provide a range of medicinal qualities, including as antioxidant, immunostimulant, antiaging, energetic, and adaptogenic effects and this due to the presence of many components in these fruits include some polysaccharides, carotenoids, flavonoids, terpenoids, vitamins B and C, and the mineral germanium. The plant fruit and leaves were extracted by maceration method and then the extracts subjected to tyrosinase inhibition assay to investigate the depigmentation of the extracts . the result cleared that the L. barbarum have a good tyrosinase inhibition activity.