Effect of Nanoparticles against Protuse Mirabilis Bacteria Isolated From Urinary Tract Infections

Abstract

The study dealt with the collection of clinical samples from patients with urinary tract infections from the patients and visitors to Samarra General Hospital during the period from October 26/10/2021 until February 3/2/2022, where 130 isolates were collected, isolated and diagnosed, and the results of the culture tests showed The biochemical return of 24 P. mirabilis isolates, IMVC tests and sensitivity tests were performed on them against 10 antibiotics by way of disc diffusion on Muller Hinton's medium. mirabilis The percentage of resistance of P. mirabilis bacteria to β-lactams represented by the antagonist Ampicillin was 87.55%, while for Ciprofloxacin 75%, Cefotaxime 79.16%, Tetracycline recorded the highest resistance by 100%, Genmicin100% and Genmicin70% 83%, and Amikacin by 91.66%, while the anti-quinolines represented by Nalidixic Nalidixic acid with a percentage of 87.5%, while the percentage of chloramphenicol was also high by 95.83%, while imipemen was the lowest by 12.5%. Also, the silver nanomaterial (taken ready) was studied on the growth of isolates and by the method of diffusion by digging. The results showed that there is a clear effect of the nanomaterial on the tested bacterial isolates, and the rate of inhibition diameters was 17-22 mm, and the results of the current study showed the ability of silver nanoparticles (AgNPs) to inhibit Bacterial growth of the tested isolates under study with different diameters depending on the concentration of the substance, as the diameter of the inhibition increased with the increase in concentration.