The Origin of Allergic Diseases and Modern Clinical Diagnostic Methods

Abstract

Allergy (from the ancient Greek ἄlós - "other, other, alien" and ἔrgón - "exposure") is a hypersensitivity of the body's immune system to an allergen with repeated exposure to an organism previously sensitized by the allergen. The term "allergy" was introduced in 1906 by the Viennese pediatrician Clemens von Pirquet. He noticed that the symptoms observed in some of his patients could be caused by environmental dust, pollen, or certain types of allergens. food. For a long time, it was believed that hypersensitivity develops due to a dysfunction of immunoglobulin E, but it soon became clear that several mechanisms involving various chemicals lead to the appearance of many of the symptoms previously classified as "allergy".