An Expository Review on 3D Bioprinting Technique with Comparison of Polysaccharide& Graphene Hydrogels as Bioink and Other Properties in Medical Applications

Abstract

3D Bioprinting” or “bioprinting” is a form of additive manufacturing that uses cells and biomaterials instead of traditional metals and plastics to create 3D constructs that are functional 3D tissues. These biomaterials called bioinks, and they mimic the composition of our tissues.

The applications of hydrogels coupled with 3-dimensional (3D) printing technologies represents a modern concept in scaffold development in tissue engineering. Hydrogels based on natural biomaterials extensively used for this purpose. This is mainly due to their excellent biocompatibility, inherent bioactivity, and special microstructure that supports tissue regeneration.

For these characteristics for polysaccharide, advanced researchs have done to find new traits, developing, or enhancing the possible disadvantages. For that, here in this project we focus on graphene hydrogel as a new carbon-based nanomaterial, which has exhibited unique advantages in significantly improving the combination properties of traditional polymer hydrogels. The specific properties of graphene, such as high electrical conductivity, high thermal conductivity and excellent mechanical properties, have made graphene not only a gelator to self-assemble into the graphene-based hydrogels (GBH) with extraordinary electromechanical performance, but also a filler to blend with small molecules and macromolecules for the preparation of multifunctional GBH. According to these, information this review also focus on briefly describe the origins and basic principles of 3D bioprinting using these two types of hydrogel and comparison their properties and applications.